EARLY LIFE IMPRINTS THE HIERARCHY OF T CELL CLONE SIZES

Early life imprints the hierarchy of T cell clone sizes

The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors.While clonal selection in Outdoor Rocking Chair response to particular antigens has been studied in detail, it is unknown how a lifetime of exposures to many antigens collectively shape the immune repertoire.Here, using mathematical modeling and st

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Exploring the acute myeloid leukaemias

The acute myeloid leukemias are genetically a diverse group of neoplasm with varied clinical behavior and response to treatment.Advances in immunophenotyping, cytogenetics and molecular genetics have resulted in better understanding of their genesis.Risk stratification of different variants is now emerging.Therapy strategies are now increasingly be

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Technology as a Medium of Ethics and Culture

In the opening of this paper I argue, contrary to a notion commonly found in the humanities and social sciences above all, and ironically yet not any less resolutely for all that, that in fact nature still exists.Subsequently I criticize the arguably more latigo and billet straps prevalent conviction that culture stands in opposition to nature.In c

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